Large-scale of wireless sensors are distributed to monitor smart grid equipment and user,s operating status information in smart grid. The original monitoring data are all collected to data processing center. And it brings huge data traffic pressure for communication network. Thus it is necessary to use data aggregation strategy in the process of data collection to reduce data traffic greatly, and reduce the overhead of communication network. This paper proposes asynchronous distributed aggregation layout construction algorithm based on hierarchical clustering. Firstly, a collection tree is constructed with the distance of all the nodes based on hierarchical clustering. Then the optimal numbers of clusters and group are calculated. And then, this paper selects the optimal aggregation nodes and constructs the best transmit topology with asynchronous distributed strategy. Finally, the simulation experiment shows that the algorithm could find the data aggregation mode of minimum cost quickly, and improve the efficiency for data collection in smart grid.