A Neural Electrophysiological Detecting System Based on Microelectrode Array
Lin Nan-sen①② Song Yi-lin①② Liu Chun-xiu① Cai Xin-xia①
①(State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, China) ②(Graduate University of Chinese Academy of Sciences, Beijing 100190, China)
Abstract：The development of a 16-channel electrophysiological signal detecting system based on the microelectrode array is described. The detecting system consists of hardware and software components, and the hardware can be divided into the following three modules: Microelectrode array interface module, which is used for connection of the micro-electrode array and the detecting system; Multi-channel signal amplification module, which is used for signal amplification; Data acquisition module, which is used for high speed data acquisition. The software design uses multi-threaded and multi-caching technology to ensure the data’s real-time observation and analysis. The main parameters of the detecting system are tested, and the laboratory-made microelectrode array is used for the detection of acute hippocampus slices. The system,s input noise Vrms is less than 2 μV, total gain of the amplifier is 1000, frequency band is 10-3000 Hz. The neural electrophysiological signals of brain slice are successfully detected. With the proper design of hardware and software system, the voltage revolution of system can attain 0.6 μV which can meet the demand of neural electrophysiological signal detection.
林楠森, 宋轶琳, 刘春秀, 蔡新霞. 神经电生理微电极阵列检测系统研制[J]. 电子与信息学报, 2011, 33(8): 2028-2032.
Lin Nan-Sen, Song Yi-Lin, Liu Chun-Xiu, Cai Xin-Xia. A Neural Electrophysiological Detecting System Based on Microelectrode Array. , 2011, 33(8): 2028-2032.
2011, Vol. 33 
